Weir, B. S. (2008). Population genetics: theory and applications. Sinauer Associates.
: While mathematically demanding, it is structured to guide a student through the derivation of key formulas, such as the Hardy-Weinberg equilibrium and diffusion equations. Content Highlights an introduction to population genetics theory pdf
Searching for " An Introduction to Population Genetics Theory " usually refers to the classic textbook by James F. Crow and Motoo Kimura Weir, B
Crow and Kimura rescue the abstract concept of F-statistics from pure math and make it biological. "F" measures the probability that two alleles are identical by descent. It is the currency of relatedness. When you read their derivation, you realize that every mating is, to some tiny degree, incestuous—and that this dictates the entire genetic load of a species. Population genetics: theory and applications
They use calculus to describe the stochastic (random) fate of a single mutation. They treat a population of millions as a single "effective size" (Ne). They force you to accept a terrifying truth: